General Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children with Cancer

نویسندگان

  • A Ghasemi
  • M Gharavi Fard
  • AR Sabzevari
چکیده

BACKGROUND Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. MATERIALS AND METHODS In this prospective observational study, two hundred and two children with cancer were enrolled. All patients received propofol 2.5 mg /kg and fentanyl 1 µg/kg. After adequate anesthesia, procedures were performed by a pediatric oncologist. All anesthesia complications were classified into two groups: Intraoperative and Postoperative complications. Complications which were recorded include: abnormal age-specific bradycardia (≤20 × baseline), decrease in arterial oxygen saturation (≤90%), laryngospasm, vomiting, agitation, headache, hypothermia (<35 C°), hyperthermia (>37/8 C°), signs of allergy, traumatic LP (bloody), and unusual local bleeding. RESULTS In this study, 118 males and 84 females underwent 623 general anesthetic procedures with a median of 3 procedures per patient. Intraoperative period complications occurred in 48 of total 623 procedures (7.7 %). The most common complications were traumatic LP, bradycardia and decrease in arterial oxygen saturation which occurred in 25, 6 and 6 cases, respectively. Postoperative period complications occurred in 74 (11.9%) cases. The most common complications were vomiting, agitation and headache, decrease O2 saturation and bradycardia. CONCLUSION General anesthesia by propofol and fentanyl may be a good choice for short-term painful procedures in children undergoing treatment for bone marrow aspiration/biopsy and intratechal injection.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

General Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children with Cancer

Abstract Background Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. Materials and Methods In this prospective observational ...

متن کامل

General Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children

Background  Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. Methods In this prospective observational study, two hundred and ...

متن کامل

Role of Anesthesia in Performing Invasive Procedures for Children with Malignancy

Background: Pediatric oncology patients frequently need several painful procedures during their diagnostic and therapeutic process. During the past decades, most centers abroad have developed safe and effective protocols for procedural sedation and analgesia in children. This report describes procedural sedation and analgesia as performed in pediatric oncology unit and tries to report success o...

متن کامل

Ketofol for bone marrow aspiration and lumbar puncture in Children with ALL

Abstract Background Ketofol is usually using as a sedative drug during painful procedures now. That Provides sedation, analgesia and rapid recovery. The aim of this study was to compare the efficacy, respiratory and hemodynamic profiles, and side effects of two various combination of ketamine and propofol in patients undergoing bone marrow aspiration (BMA) and lumbar puncture (LP). Materials...

متن کامل

Sedative and Analgesic efficacy of Propofol-Ketamine and Propofol-Remifentanil During Painful Procedures in Children with Acute Lymphoblastic Leukemia

Background: Lumbar puncture (LP) and bone marrow aspiration or biopsy in pediatric patients with hematological diseases is often repeated at regular intervals. These procedures are painful and unpleasant and bring a lot of stress for the children and their families. This study aimed to compare the effectiveness of two drug combinations of propofol-ketamine and propofol-remifentanil in children ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2013